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These therapies aim to restore or enhance the gut microbiota, which plays a crucial role in UC pathogenesis

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In conclusion, MQC is an integrated network that monitors mitochondrial quality and works in concert to maintain mitochondrial homeostasis by coordinating various processes, including mitochondrial biogenesis, mitochondrial autophagic degradation, and the balance of mitochondrial dynamics (fission, fusion) (Zhou et al., 2023)

Wang, Y., Qiao, M., Mieyal, J.J., Asmis, L.M., and Asmis, R., Free Radical Biol

The effects of microbial-derived metabolites on kidney disease Evidence shows that SCFAs mitigate renal fibrosis by suppressing the expression of the pro-fibrotic chemokine monocyte chemoattractant protein-1 (MCP-1) induced by tumor necrosis factor- (TNF-) ( Figure 3 ) [88]